Single?use (SU) technology has become an important part of biotechnology research and commercial biomanufacturing. Sustainability is a long?term holistic approach that evaluates how biological systems remain diverse and productive over time, and also considers concerns of a more immediate and nonbiological focus. Sustainability emphasizes the ability to use natural resources in a way that indefinitely protects the integrity (and limits the fouling or depletion) of existing biological and other environmental systems. Several initial environmental analyses performed for SU biologics production illustrated the need for rational and comprehensive analysis techniques such as life cycle assessment to understand the total, specific, and “cradle?to?grave” environmental strain imposed by both durable and SU approaches. “End?of?life” considerations are a big part of most discussions about SU and the environment because of the visibility of the pre and post?process material.
SOURCE: Whitford, W. Petrich, M. Flanagan, W. “Environmental Impacts of Single?Use Systems.” Single?Use Technology in Biopharmaceutical Manufacture, 2019.
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